ea0003oc42 | Neuroendocrinology | BES2002
Stanley S
, Davies S
, Small C
, Gardiner J
, Ghatei M
, Smith D
, S#R##Bloom|#
The hypothalamic melanocortin 4 receptor, its endogenous agonist, alpha melanocyte stimulating hormone and the endogenous antagonist, Agouti related peptide (Agrp) regulate energy homeostasis. However, the physiological role of the hypothalamic melanocortin receptor, MC3-R and its agonist, gamma MSH are currently unknown. We have previously shown that the MC3/4 agonist, a-MSH has no effect on GnRH release from hypothalamic explants and does not influence plasma gonadotrophins ...